For Clinical Trial Sponsors & CROs
Connect the Right Patients to the Right Trials, Faster
TrialBridge uses AI and native FHIR interoperability to turn fragmented medical records into structured, coded, matchable data — so eligible patients aren't missed.
The Problem
The Bottleneck in Clinical Trials
Critical medical data — essential for finding the right patients — is often locked away in unstructured text like clinical notes, pathology reports, and imaging summaries. Manual extraction and interpretation slow research, add cost, and let eligible patients slip through.
Slow & Error-prone
Manual chart review is time-consuming and inconsistent, leading to variable data quality and missed matches.
Startup Delays
Manual screening steps add weeks to trial initiation, pushing back time-to-market and inflating cost.
Hinders Matching
Unstructured clinical data blocks automated screening at scale, so matching stays subjective and incomplete.
Limits Data Use
Valuable secondary insights stay locked in free text — untapped for trial design and patient selection.
The result is a critical bottleneck across the research landscape — one that manual processes can't clear.
How It Works
From Records to Ranked Matches in Three Steps
A single pipeline that connects your data, codes it, and returns prioritized candidates.
Connect
Ingest structured and unstructured records from your EMR, CTMS, and documents — with privacy-first, zero-egress deployment options.
Code & Structure
AI extracts and codes the data into every relevant ontology (SNOMED CT, ICD-10, LOINC, RxNorm) as native FHIR, building longitudinal patient records.
Match & Rank
Patients are matched against trial criteria and ranked by an explainable Trial Fitment Score, so your team reviews the best candidates first.
The Solution
From Bottleneck to Breakthrough
TrialBridge automates and enhances patient–trial matching with advanced AI (LLMs & GNNs) and native FHIR interoperability — turning fragmented data into precise, efficient recruitment.
How TrialBridge Delivers Value
Accelerated Recruitment
By automating extraction of structured data from clinical notes and EMRs, TrialBridge cuts the time spent on manual chart review and surfaces candidates faster than manual methods.
Superior Matching Accuracy
A multi-modal AI approach interprets complex eligibility criteria and patient characteristics for more precise matching — reducing screening failures and improving the patient experience.
Optimized Cohorts
Better matching means better cohorts. Aligning enrolled patients closely with the protocol's intent supports more homogenous study groups and a stronger foundation for evaluating efficacy.
Built for Scale & Integration
A modern cloud architecture and native FHIR capabilities handle growing data volumes and keep data flowing between your existing systems (EMRs, CTMS) and TrialBridge.
The Technology
Our Multi-Modal AI & FHIR-Native Core
Six capabilities working together to deliver accurate, explainable, and interoperable matches.
Fine-Tuned LLMs
Semantic understanding for precise data extraction from unstructured medical texts.
Graph Neural Networks
Capture complex relationships between medical concepts for deeper insight and better matching.
Multi-Ontology Coding
Every record coded into all relevant ontologies — SNOMED CT, ICD-10, LOINC, RxNorm — as native FHIR.
Explainable Fitment Scores
Transparent, quantitative Trial Fitment Scores for ranking and prioritizing potential participants.
Privacy & Security
HIPAA-aligned with end-to-end encryption and a zero-data-egress deployment option — your data never has to leave your environment.
Modular Architecture
Customizable components that adapt to your specific workflow and integration needs.
These components work together, delivering more accurate, explainable, and interoperable results than siloed approaches.
Our Team
Driven by Experts
A founding team spanning clinical research, healthcare AI, and interoperable systems.
Get Started
See TrialBridge in Action
Ready to accelerate your trial recruitment? Request a personalized demo to see how TrialBridge streamlines patient matching for your therapeutic area. We'll respond within two business days.
Prefer email? Reach us directly at info@trialbridge.org.